I just found an archive of some very cool audio interviews at Comic Geek Speak -
check out the full list 
hereHere are some personal picks from the list (though I have yet to listen to all of these):
• 
Mark Bagley - had a damn fine run on Amazing Spiderman in the 90's
• 
Gene Colan - a Marvel legend
• 
Joe Kubert - another comic art legend.  Quite possibly best known for Sgt. Rock
• 
Erik Larsen - for me, Erik Larsen just might be the definitive Spider-man artist.  It was during his run on Amazing that I really started paying attention to comics.
• 
Stan Lee - The Man, himself.  'Nuff said.
• 
Paul Pope - see my previous post for more Paul Pope links
• Dave Sim 
interview #1• Dave Sim 
interview #2About a year or two ago I read Cerebus straight through in its entirety.  I think you should too.
• 
Walt Simonson - The Mighty Thor